Recommended 2 Pumps

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

Name: NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー
Brand: Renue Store
SKU: 850055685215
Price: 9000.0 JPY
Availability: InStock

便利な認知力の向上

¥9,000 JPY

商品バリエーション

配送料はチェックアウト時に計算されます。

外出先で便利な製品をお探しなら、当社の NAD+ 鼻スプレーがメインの NAD+ サプリメントの完璧な補完品となります。

NAD+ 点鼻スプレーは、広範囲の全身循環ではなく、脳に焦点を絞った標的送達を実現します。他のすべての送達方法よりも、認知機能と脳の混乱に強力な効果を発揮するように設計されています。†

Recommended 2 Pumps

詳細を表示する

Clinical Trial: Evaluating the Efficacy of Liposomal NMN

A double-blind, placebo-controlled clinical trial was conducted with 15 healthy men aged 40 and older to measure the effects of NMN supplementation. Participants were randomly assigned to one of three groups (5 per group) and took their assigned supplement daily after breakfast for four weeks.

Placebo Group: Maltodextrin (4g/day)
Standard NMN Group: Non-liposomal NMN (350 mg/day)
Liposomal NMN Group: Liposomal NMN (350 mg/day)

Blood NAD+ levels were measured at four time points:

1. Before supplementation (baseline)
2. One hour after the first dose
3. After four weeks of daily supplementation
4. Four weeks after stopping supplementation

This study design allowed researchers to assess not just how effectively each form of NMN raised NAD+ levels, but also how long those effects persisted after supplementation ended.

NAD+ Is Essential to Life ...but declines with age

NAD+ precursors and defenders can protect youthful NAD+ levels to maintain healthy energy, strength, and cognition.

Liposomal NMN Increased Blood NAD+ Levels By 84%

After four weeks of supplementation, the Liposomal NMN Group exhibited an 84% increase in blood NAD+ levels, rising from 28.6 µM (baseline) to 52.5 µM.

Although NAD+ levels declined four weeks after participants stopped supplementation, they remained elevated at 36 µM compared to the baseline of 28.6 µM.

Encapsulated NMN Boosted NAD+ More Effectively Than Standard NMN

Among all groups, Liposomal NMN produced the greatest increase in NAD+ levels after four weeks, outperforming both Standard NMN and placebo.

Learn More about the Study HERE

Which NAD+ Precursor Is Best?

NAD+

This central coenzyme is directly involved in redox reactions and serves as a substrate for energy production enzyme activity, including sirtuins and poly(ADP-ribose) polymerases (PARPs), which regulate cellular metabolism, DNA repair, and epigenetic modifications.

NMN

This NAD+ precursor, which is directly converted to NAD+ through the NMNAT enzyme in the Salvage Pathway, has been shown to effectively increase intracellular NAD+ levels in numerous clinical trials, thereby enhancing mitochondrial function, energy production, and the activity of NAD+-dependent enzymes.

NR

This NAD+ precursor, which is converted to NAD+ through the Preiss-Handler Pathway, has also demonstrated the ability to increase NAD+ levels in cells. It supports cellular repair mechanisms, particularly those involved in DNA damage response and oxidative stress mitigation. By buttressing NAD+ levels, NR promotes the activation of sirtuins and PARPs, which protect genomic stability and regulating cellular metabolism.

Trigonelline

Trigonelline promotes cellular NAD+ production differently than NMN or NR. This methylated form of niacin offers several advantages: exceptional stability in the bloodstream, slow release into target tissues, non-flushing, protection against stomach digestion, and direct NAD+ increase in muscle tissues.

Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream. (1)

This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

Research

Liposomes Increase Bioavailability

With our Liposomal products, approximately 90% of the payload reaches the bloodstream intact, regardless of what the payload is.

For example, with our Liposomal Green Tea Extract around 90% of the EGCG reaches the bloodstream.

With regular Green Tea extract, around 9% of EGCG reaches the bloodstream.

Hence the study below shows it is about 10x more bioavailable.

Regular Apigenin is around 30% bioavailable, so you can expect our Liposomal Apigenin to be approximately 3x more bioavailable than regular Apigenin.

Although we don't have research on bioavailability of all our Liposomal products, below we show research that demonstrates increased bioavailability of 3 to 40x when using liposomes in some of the most popular supplements we produce.

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Frequently Asked Questions

I am not sure if it is refreshing my youth

I am not sure if it is refreshing my youth. I can say it has given me a little energy boost.

I noticed results immediately (that day)

I noticed results immediately (that day)! I highly recommend if you're a woman over 40 and need an extra boost to keep the routine of work, workout and family responsibilities balanced!

My wife has bulbar-onset ALS

My wife has bulbar-onset ALS, and we were pleased to see that this product helped support our stem cell exosomes treatments.

El atomizador se daño y todavia me queda la mitad del producto

El atomizador se daño y todavia me queda la mitad del producto.

I like the ingredients but the actual spray bottle doesn’t work well

I like the ingredients but the actual spray bottle doesn’t work well. Been buying it for over a year and plan to stop because two times in a row the bottle spray mechanism fails. Too bad…

1 2 3

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

便利な認知力の向上

Clinical Trial: Evaluating the Efficacy of Liposomal NMN

NAD+ Is Essential to Life ...but declines with age

Liposomal NMN Increased Blood NAD+ Levels By 84%

Encapsulated NMN Boosted NAD+ More Effectively Than Standard NMN

Which NAD+ Precursor Is Best?

NAD+

NMN

NR

Trigonelline

Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream. (1)

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

Liposomes Increase Bioavailability

NAD⁺、NMN、NR（リポソーム）配合の鼻スプレー

Certifications

Supported by Science

Purest Ingredients

Advanced Testing

Certified Labs

Strength and Purity Certification

Gold Standard Testing

Nasal NAD+ Report

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