Hesperidin is a flavonoid, a type of plant compound that has been shown to have a wide range of health benefits.†
It is found primarily in citrus fruits, such as oranges, lemons, grapefruit, and limes.†
Hesperidin exhibits anti-inflammatory and antioxidant activity, protecting cells from two key contributors to the onset of age-related and chronic diseases: inflammation and oxidative stress.†
Heart Health
A meta-analysis of 13 studies reported that Hesperidin supplementation decreased blood cholesterol levels, the inflammatory molecule TNF-α, and systolic blood pressure.†
Blood pressure
In a clinical trial, adults with type 2 diabetes showed significant improvements in blood pressure, inflammation, and total antioxidant capacity (a measure indicating the ability to neutralize harmful free radicals) after supplementing with Hesperidin for 6 weeks.†Blood pressure
In a clinical trial, adults with type 2 diabetes showed significant improvements in blood pressure, inflammation, and total antioxidant capacity (a measure indicating the ability to neutralize harmful free radicals) after supplementing with Hesperidin for 6 weeks.†
Inflammation
An evaluation of 18 clinical trials in a meta-analysis revealed Hesperidin reduced several markers of inflammation and the levels of MDA, a marker of damage to fat important for cell function and structure.†Inflammation
An evaluation of 18 clinical trials in a meta-analysis revealed Hesperidin reduced several markers of inflammation and the levels of MDA, a marker of damage to fat important for cell function and structure.†
Blood Vessel Function
A 3-week clinical trial showed Hesperidin improved blood flow and reduced the levels of inflammatory markers in adults with metabolic syndrome.† In a trial with overweight men, drinking a glass of orange juice daily or supplementing with Hesperidin for four weeks improved blood flow after meals, indicating improved blood vessel function.†
Learn More About Liposomal Delivery
Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream. (1)
This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.
Are any of your liposomal products heat-sensitive?
The liposomal powder capsule products are not heat sensitive.
The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.
What's the difference between Liposomal vs. Delayed & Extended Release Caps?
Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.
Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).
In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.
What are the liquid and powdered liposome differences in bioavailability and stability?
Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.
Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.
What are the benefits of liposomal delivery? Are liposomes really better?
When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.
A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.
Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.
The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.
Great quality and definitely working.I Definitely will be keeping this in my supplement rotation.
K
Kim Mackey
Lipo Hesperidin
Hesperidin can be useful for someone with type 2 diabetes. See link below.
Hesperidin Supplementation Alleviates Oxidative DNA Damage and Lipid Peroxidation in Type 2 Diabetes: A Randomized Double-Blind Placebo-Controlled Clinical Trial