Scientific Evidence Library

article-page-carousel-item--Emerging Strategies, Applications, and Challenges of Targeting NAD⁺ in the Clinic: A Review

Emerging Strategies, Applications, and Challeng...

Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a master regulator of health, supporting DNA repair, epigenetic programming, immune responses, and mitochondrial function....

Emerging Strategies, Applications, and Challeng...

Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a...

article-page-carousel-item--Mouse Study Shows Organ-Specific Effects of NAD+ Modulation on Aging

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers, and...

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers...

article-page-carousel-item--NMN Protects Mitochondria and Reduces Heart Injury in Septic Mice

NMN Protects Mitochondria and Reduces Heart Inj...

This study demonstrated that NMN protected heart function in septic mice by reducing mitochondrial free radical production and correcting abnormal protein modifications in mitochondria.

NMN Protects Mitochondria and Reduces Heart Inj...

This study demonstrated that NMN protected heart function in septic mice by reducing mitochondrial free radical...

article-page-carousel-item--NMN Enhanced Mitochondrial Stress Response and Improved Cognition in an Alzheimer’s Mouse Model

NMN Enhanced Mitochondrial Stress Response and ...

“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by which NAD+-boosting agent nicotinamide mononucleotide (NMN) regulates MSR in AD models.”

NMN Enhanced Mitochondrial Stress Response and ...

“We combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by...

article-page-carousel-item--Liposomal Glutathione Reduced Oxidative Stress and Improved Immune Function in Humans

Liposomal Glutathione Reduced Oxidative Stress ...

Collectively, these preliminary findings support the effectiveness of daily liposomal GSH administration at elevating stores of GSH and impacting immune function and levels of oxidative stress.

Liposomal Glutathione Reduced Oxidative Stress ...

Collectively, these preliminary findings support the effectiveness of daily liposomal GSH administration at elevating stores of...

article-page-carousel-item--NMN Enhances Cellular Protection and Cognitive Function in Alzheimer’s Disease Mice

NMN Enhances Cellular Protection and Cognitive ...

Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory Reduced neuronal injury Promoted clearance of abnormal tau protein Activated autophagy Enhanced antioxidant defense...

NMN Enhances Cellular Protection and Cognitive ...

Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory...

article-page-carousel-item--NMN Protects Skin and Improves Prognosis in Psoriatic Mice

NMN Protects Skin and Improves Prognosis in Pso...

“We demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and improve therapeutic prognoses by activating the SIRT1 pathway.”

NMN Protects Skin and Improves Prognosis in Pso...

“We demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and...

article-page-carousel-item--Study Shows NMN Protects Against Lung Damage in Mice

Study Shows NMN Protects Against Lung Damage in...

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

Study Shows NMN Protects Against Lung Damage in...

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure...

article-page-carousel-item--Study Finds Liposomal Berberine Improves Glucose, Lipids, and Inflammation in Rats

Study Finds Liposomal Berberine Improves Glucos...

“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme...

Study Finds Liposomal Berberine Improves Glucos...

“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited...

article-page-carousel-item--Heart Disease Related to Accumulation of DNA Damage and Oxidative Stress

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...