Combination Product

Serving Size 2 Capsules

120 Capsules Allergen-Free

LIPO NAD⁺ 完整

Name: NAD⁺ Complete（脂质体）
Brand: Renue Store
SKU: 656165996551
Price: 129.95 AUD
Availability: InStock

全面的 NAD+ 支持

$129.95 AUD

结账时计算的运费。

LIPO NAD⁺ Complete 是一种强大的 4 合 1 NAD⁺ 增强剂，采用我们专有的粉末状脂质体，可保护 NAD⁺、NMN、NR 和葫芦巴碱免受消化酶的侵蚀，并将它们带入血液进行有针对性的全身输送。

产品多属性

Combination Product

Serving Size 2 Capsules

120 Capsules Allergen-Free

LIPO NAD⁺ Complete Details

LIPO NAD+ Complete is designed to deliver the most potent dose of NAD+, NMN, NR and Trigonelline via nanoscale liposomes to increase your body’s NAD+ levels.

While there is a lot of uncertainty about the pathways NAD⁺ and NAD⁺ precursors take in the body, we do know that there are differences between them, and they have affinity for different tissues. We believe the most effective protocol to increase NAD⁺ is through targeting all of these pathways.

Four-In-One Capsule

We provide all four in one capsule to better address all parts of the body that may benefit from restoring NAD⁺ levels.

NAD+: This central coenzyme is directly involved in redox reactions and serves as a substrate for energy production enzyme activity, including sirtuins and poly(ADP-ribose) polymerases (PARPs), which regulate cellular metabolism, DNA repair, and epigenetic modifications.
NMN: This NAD+ precursor, which is directly converted to NAD+ through the NMNAT enzyme in the Salvage Pathway, has been shown to effectively increase intracellular NAD+ levels in numerous clinical trials, thereby enhancing mitochondrial function, energy production, and the activity of NAD+-dependent enzymes.
NR: This NAD+ precursor, which is converted to NAD+ through the Preiss-Handler Pathway, has also demonstrated the ability to increase NAD+ levels in cells. It supports cellular repair mechanisms, particularly those involved in DNA damage response and oxidative stress mitigation. By buttressing NAD+ levels, NR promotes the activation of sirtuins and PARPs, which protect genomic stability and regulating cellular metabolism.
Trigonelline: Trigonelline promotes cellular NAD+ production differently than NMN or NR. This methylated form of niacin offers several advantages: exceptional stability in the bloodstream, slow release into target tissues, non-flushing, protection against stomach digestion, and direct NAD+ increase in muscle tissues.

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NAD+ 对生命至关重要……但会随着年龄的增长而下降

NAD+ 前体和防御者可以保护年轻的 NAD+ 水平，以维持健康的能量、力量和认知。

NAD+ 对生命至关重要……但会随着年龄的增长而下降

NAD+ 前体和防御者可以保护年轻的 NAD+ 水平，以维持健康的能量、力量和认知。

哪种 NAD+ 前体最好？

NAD+

这种中心辅酶直接参与氧化还原反应，并作为能量产生酶活性的底物，包括 sirtuins 和聚（ADP-核糖）聚合酶 (PARPs)，它们调节细胞代谢、DNA 修复和表观遗传修饰。

纳米二核苷酸

这种 NAD+ 前体通过 Salvage 途径中的 NMNAT 酶直接转化为 NAD+，已被大量临床试验证明可以有效提高细胞内 NAD+ 水平，从而增强线粒体功能、能量产生和 NAD+ 依赖性酶的活性。

天然橡胶

这种 NAD+ 前体通过 Preiss-Handler 途径转化为 NAD+，还表现出提高细胞中 NAD+ 水平的能力。它支持细胞修复机制，特别是那些涉及 DNA 损伤反应和氧化应激缓解的机制。通过支持 NAD+ 水平，NR 促进 sirtuins 和 PARP 的激活，从而保护基因组稳定性并调节细胞代谢。

葫芦巴碱

葫芦巴碱促进细胞 NAD+ 生成的方式与 NMN 或 NR 不同。这种甲基化形式的烟酸具有多种优势：在血流中具有出色的稳定性、缓慢释放到目标组织中、不会引起潮红、防止胃消化以及直接增加肌肉组织中的 NAD+。

提高生物利用度

脂质体递送

脂质体是一种革命性的方法，将活性成分封装在磷脂“气泡”中，以保护活性成分并将其直接输送到组织细胞，然后通过血液到达。（1）这样可以使成分被吸收和利用，而不会在胃中被破坏。

服用任何补充剂的目的是确保其进入血液。然而，由于传统口服胶囊的吸收率和生物利用度较低，活性成分在通过胃肠道时会失去大部分效力，或者根本无法在小肠中吸收。大多数未经利用就通过肠道或肾脏排出体外。（2）

脂质体递送可实现活性成分的定向和完全吸收，具有延迟释放效果，与所有其他营养递送方法不同。关键营养素在血液中的循环时间增加，显著提高了生物利用度。活性物质的生物利用度越高，其对身体的影响就越大。

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研究

脂质体提高生物利用度

使用我们的脂质体产品，无论有效载荷是什么，大约 90% 的有效载荷都能完整地到达血液。

例如，我们的脂质体绿茶提取物中约 90% 的 EGCG 能够到达血液。

通过常规绿茶提取物，约有9% 的 EGCG 会进入血液。

因此，下面的研究表明它的生物利用度大约高出 10 倍。

常规芹菜素的生物利用度约为 30% ，因此，您可以预期我们的脂质体芹菜素的生物利用度比常规芹菜素高出约 3 倍。

虽然我们没有对所有脂质体产品的生物利用度进行研究，但下面我们展示的研究表明，在我们生产的一些最受欢迎的补充剂中使用脂质体时，生物利用度提高了 3 到 40 倍。

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常见问题

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.