90 Capsules Allergen-Free
250 mg Each of LIPO Berberine
Serving size 1 capsule
小檗碱(脂质体)
小檗碱(脂质体)
心脏保护和代谢
90 Capsules Allergen-Free
250 mg Each of LIPO Berberine
Serving size 1 capsule
Details
Berberine is a bioactive compound produced in plants and has been appreciated for its health benefits for centuries.† Today, Berberine remains at the forefront of health and wellness research due to its ability to support metabolic health.†
Liposomal Delivery
The efficacy of standard formulations of Berberine is limited due to low absorption and extensive breakdown after ingestion.† A study using liposomal delivery found administration of Liposomal Berberine in rats increased retention time in circulation from .42 to 10 hours (23-46x).†
The figure below shows the amount of liposomal Berberine formulations (yellow and orange bars) is higher in tissues and blood compared to a standard formulation (blue bar).
Standard Berberine has poor absorption and hasless than 1%oral bioavailability, meaning its levels in the blood quickly diminish after ingestion.† To address this issue, LIPO Berberine uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†
小檗碱是一种植物中产生的生物活性化合物,几个世纪以来一直因其健康益处而受到重视。† 如今,小檗碱因其支持代谢健康的能力而仍然处于健康和保健研究的前沿。†
小檗碱的脂质体递送
标准小檗碱吸收性差,口服生物利用度不到 1% ,这意味着摄入后其在血液中的浓度会迅速降低。† 为了解决这个问题,LIPO 小檗碱使用先进的脂质体输送系统,旨在提高生物利用度,实现更好的吸收,并更缓慢地释放到血液中。†
由于吸收率低且摄入后会大量分解,标准配方的小檗碱的功效有限。† 一项使用脂质体递送的研究发现,给大鼠施用脂质体小檗碱可使血液循环中的保留时间从 0.42 小时增加到 10 小时(23-46 倍)。†
下图显示,与标准制剂(蓝色条)相比,脂质体小檗碱制剂(黄色和橙色条)在组织和血液中的含量更高。
认证
科学支持
All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.
We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.
Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.
常见问题
脂质体递送
What are the benefits of liposomal delivery? Are liposomes really better?
When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.
A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.
Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.
The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.
What are the liquid and powdered liposome differences in bioavailability and stability?
Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.
Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.
What’s the difference between Liposomal vs. Delayed & Extended Release Caps?
Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.
Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).
In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.
Are any of your liposomal products heat-sensitive?
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