Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--Long Term NMN Use Extends Lifespan and Healthspan in Mice with Sex-Specific Effects

Long Term NMN Use Extends Lifespan and Hea...

5 min

Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...

5 min

Long Term NMN Use Extends Lifespan and Healthsp...

Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male...

article-page-carousel-item--Slc12a8 Transporter is Key for Efficacy of NMN in Septic Mice

Slc12a8 Transporter is Key for Efficacy of...

6 min

Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport through the Slc12a8 transporter.

6 min

Slc12a8 Transporter is Key for Efficacy of NMN ...

Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport...

article-page-carousel-item--NR Shows Ability to Promote DNA Repair and Increase Lifespan by 25% in Mice

NR Shows Ability to Promote DNA Repair and...

2 min

Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this study were shown to have an effect on lifespan in mice engineered to age...

2 min

NR Shows Ability to Promote DNA Repair and Incr...

Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this...

article-page-carousel-item--NAD+ Reduces Mutations and Incidence of Skin Cancer

NAD+ Reduces Mutations and Incidence of Sk...

3 min

NMN and NR lead to greater increases in NAD+ than NAM It has been well established that the molecules NMN and NR lead to greater increases in NAD+ levels than...

3 min

NAD+ Reduces Mutations and Incidence of Skin Ca...

NMN and NR lead to greater increases in NAD+ than NAM It has been well established...

article-page-carousel-item--Fisetin Effectively Eliminates Senescent Cells and Restores Stem Cells

Fisetin Effectively Eliminates Senescent C...

4 min

Since immune cells play such a critical role in keeping the population of senescent cells in check, senescent immune cells are a prime target of senolytic drugs. Fisetin has been...

4 min

Fisetin Effectively Eliminates Senescent Cells ...

Since immune cells play such a critical role in keeping the population of senescent cells in...

article-page-carousel-item--Heart Disease Related to Accumulation of DNA Damage and Oxidative Stress

Heart Disease Related to Accumulation of D...

2 min

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...

2 min

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...