90 Capsules Allergen-Free

250 mg Each of LIPO Berberine

Serving size 1 capsule

Berberine (Liposomal)

Name: Berberine (Liposomal) 90 Ct.
Brand: Renue Store
SKU: 656165997145
Price: 7900.0 JPY
Availability: InStock

Cardioprotection and metabolism

¥7,900 JPY

Shipping calculated at checkout.

Berberine is a natural compound shown to exert antioxidant and cardioprotective effects.† LIPO Berberine is formulated to support glucose and lipid metabolism, heart health, and overall metabolic homeostasis.†

Product variants

90 Capsules Allergen-Free

250 mg Each of LIPO Berberine

Serving size 1 capsule

Details

Berberine is a bioactive compound produced in plants and has been appreciated for its health benefits for centuries.† Today, Berberine remains at the forefront of health and wellness research due to its ability to support metabolic health.†

Liposomal Delivery

The efficacy of standard formulations of Berberine is limited due to low absorption and extensive breakdown after ingestion.† A study using liposomal delivery found administration of Liposomal Berberine in rats increased retention time in circulation from .42 to 10 hours (23-46x).†

The figure below shows the amount of liposomal Berberine formulations (yellow and orange bars) is higher in tissues and blood compared to a standard formulation (blue bar).

Standard Berberine has poor absorption and hasless than 1%oral bioavailability, meaning its levels in the blood quickly diminish after ingestion.† To address this issue, LIPO Berberine uses an advanced liposomal delivery system designed to improve the bioavailability, created for better absorption, and a slower release into the bloodstream.†

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Liposomal Delivery of Berberine

The figure below shows the amount of liposomal Berberine formulations (yellow and orange bars) is higher in tissues and blood compared to a standard formulation (blue bar).

Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream.⑴

This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.

The aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract or are simply not absorbed in the small intestine at all. The majority is excreted unused via the intestines or kidneys. ⑵

Liposomal delivery offers a targeted and complete absorption of active ingredients with a delayed‑release effect, unlike all other nutrient delivery methods. This increased circulation time of key nutrients in the bloodstream significantly improves bioavailability. The higher the bioavailability of an active substance, the more effect it has on the body.

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Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Strength and Purity Certification Gold Standard Testing Certificate of Analysis

Frequently Asked Questions

LIPOSOMAL DELIVERY

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What’s the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.

Berberine (Liposomal)