90 Capsules Allergen-Free

300 mg Each of LIPO CaAKG

Serving size 1 capsule

CaAKG (Liposomal)

Name: CaAKG (Liposomal) 90 Ct.
Brand: Renue Store
SKU: 656165996650
Price: 7700.0 JPY
Availability: InStock

Mitochondrial and metabolic health

¥7,700 JPY

Shipping calculated at checkout.

Support healthy aging, mitochondrial function & metabolic health with CaAKG, the stable form of the naturally occuring substance, Alpha-Ketoglutarate (AKG), which declines as you age.

Each 300 mg capsule of CaAKG is comprised of 60 mg Calcium and 240 mg AKG.

LIPO CaAKG is also available in our combination product, Defender.

Product variants

90 Capsules Allergen-Free

300 mg Each of LIPO CaAKG

Serving size 1 capsule

Details

Calcium Alpha-Ketoglutarate (CaAKG) works by slowing the rate of age-related DNA methylation and reducing the inflammation caused by senescent cells: two proposed reasons why we age.

CaAKG also contributes to metabolism, providing energy for cellular processes. It helps stimulate collagen and protein synthesis and influences age-related processes including stem cell proliferation. Increasing CaAKG in the body supports your liver and its detoxification abilities.

CaAKG Lowers Inflammation

CaAKG Lowers Inflammation – Shown to Increase Healthspan & Lifespan In Mice

In a study at the The Buck Institute for Research on Aging, CaAKG was shown to significantly extend the lifespan and healthspan in mice.

“We find that CaAKG promotes a longer, healthier life associated with a decrease in levels of systemic inflammatory cytokines.” ⑴

Chronic inflammation has a significant impact on NAD⁺ levels — CaAKG can lower inflammation and preserve NAD⁺ levels which may lead to a healthier, longer life.

Liposomal Delivery

LIPO CaAKG is a sustained-released liposomal delivery system that provides superior absorption of CaAKG in easy-to-swallow capsules.

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Metabolic and Mitochondrial Maintenence

Calcium Alpha-Ketoglutarate (CaAKG) works by slowing the rate of age-related DNA methylation and reducing the inflammation caused by senescent cells: two proposed reasons why we age.

Learn More About Liposomal Delivery

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream.⑴

This allows for the ingredients to be absorbed and utilized rather than being destroyed in the stomach.

The aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract or are simply not absorbed in the small intestine at all. The majority is excreted unused via the intestines or kidneys. ⑵

Liposomal delivery offers a targeted and complete absorption of active ingredients with a delayed‑release effect, unlike all other nutrient delivery methods. This increased circulation time of key nutrients in the bloodstream significantly improves bioavailability. The higher the bioavailability of an active substance, the more effect it has on the body.

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Certifications

Supported by Science

Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Strength and Purity Certification Gold Standard Testing Certificate of Analysis Certificate of Analysis

Frequently Asked Questions

LIPOSOMAL DELIVERY

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What’s the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.