Sublingual

NMNs (Fast Dissolve Sublingual Tabs) 125 mg

Name: NMNs (Fast Dissolve Sublingual Tabs) 125 mg
Brand: Renue Store
SKU: 850055685154
Price: 10900.0 JPY
Availability: InStock

Convenient NAD+ boosting sublingual tablets

¥10,900 JPY

Shipping calculated at checkout.

These tablets can be chewed or dissolved under the tongue. A percentage of the NMN is absorbed directly to the bloodstream and is available to cells throughout the body, rather than being degraded in the stomach as capsules are.

Product variants

Sublingual

Sublingual Delivery

Sublingual (under the tongue) delivery can provide rapid absorption via the blood vessels under the tongue rather than via the digestive tract. (1,2,3)

The absorption of the different molecules delivered through the sublingual route can be 3 to 10 times greater than oral route and is only surpassed by liposomal delivery and direct IV injection (3).

Research on sublingual delivery of NMN specifically, is not yet published, so the increased efficiency is not yet quantified.

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NAD+ Is Essential to Life ...but declines with age

NAD+ precursors and defenders can protect youthful NAD+ levels to maintain healthy energy, strength, and cognition.

NAD+ Is Essential to Life ...but declines with age

NAD+ precursors and defenders can protect youthful NAD+ levels to maintain healthy energy, strength, and cognition.

Which NAD+ Precursor Is Best?

NAD+

This central coenzyme is directly involved in redox reactions and serves as a substrate for energy production enzyme activity, including sirtuins and poly(ADP-ribose) polymerases (PARPs), which regulate cellular metabolism, DNA repair, and epigenetic modifications.

NMN

This NAD+ precursor, which is directly converted to NAD+ through the NMNAT enzyme in the Salvage Pathway, has been shown to effectively increase intracellular NAD+ levels in numerous clinical trials, thereby enhancing mitochondrial function, energy production, and the activity of NAD+-dependent enzymes.

NR

This NAD+ precursor, which is converted to NAD+ through the Preiss-Handler Pathway, has also demonstrated the ability to increase NAD+ levels in cells. It supports cellular repair mechanisms, particularly those involved in DNA damage response and oxidative stress mitigation. By buttressing NAD+ levels, NR promotes the activation of sirtuins and PARPs, which protect genomic stability and regulating cellular metabolism.

Trigonelline

Trigonelline promotes cellular NAD+ production differently than NMN or NR. This methylated form of niacin offers several advantages: exceptional stability in the bloodstream, slow release into target tissues, non-flushing, protection against stomach digestion, and direct NAD+ increase in muscle tissues.