Research
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation of cells. Its secondary mediator, insulin-like growth factor 1 (IGF-1), is produced in response...
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation...
Study Shows NMN Supplementation or CD38 Inhibit...
CD38 Deficiency Alleviates Ang II-Induced Vascular Remodeling By Inhibiting Small Extracellular Vesicle-Mediated Vascular Smooth Muscle Cell Senescence In Mice (Lu Gan, June 2021) In this study, researchers investigated the impact...
Study Shows NMN Supplementation or CD38 Inhibit...
CD38 Deficiency Alleviates Ang II-Induced Vascular Remodeling By Inhibiting Small Extracellular Vesicle-Mediated Vascular Smooth Muscle Cell...
Bacteria in Gastrointestional Tract Metabolize ...
This recently published research by Drs. Lindsay Wu, David Sinclair and others examined the pathways that oral NMN takes to becoming NAD+ in mice. It confirmed some aspects of earlier...
Bacteria in Gastrointestional Tract Metabolize ...
This recently published research by Drs. Lindsay Wu, David Sinclair and others examined the pathways that...
CD73 utilization shows importance of NMN to res...
This recent study found that in endothelial cells, the extracellular conversion of NMN to NR by CD73 enzyme in the cell membrane is a key mechanism to maintain intracellular NAD+...
CD73 utilization shows importance of NMN to res...
This recent study found that in endothelial cells, the extracellular conversion of NMN to NR by...
Case Study on Liposomal NMN Shows Positive Impa...
“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme...
Case Study on Liposomal NMN Shows Positive Impa...
“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited...
How NAD+ Boosts ATP and What it Means for Healt...
Much of the attention on the benefits of restoring NAD+ levels focus on its role in activating sirtuins. However, scientific research shows that NAD supplementation has a clear beneficial effect...
How NAD+ Boosts ATP and What it Means for Healt...
Much of the attention on the benefits of restoring NAD+ levels focus on its role in...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing...
NAD+ IV increases NAD+ levels in blood plasma 4...
This study was just published that documented changes in plasma and urine levels of NAD+ and its metabolites during and after 750 mg NAD+ intravenous (IV) infusion. A Pilot Study...
NAD+ IV increases NAD+ levels in blood plasma 4...
This study was just published that documented changes in plasma and urine levels of NAD+ and...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of 3 μmole/min all exogenously infused NAD+ was rapidly and completely removed from the plasma...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of...
NAD+ is the Transport Molecule Used by the Body...
The benefits noted from supplementation with NR in recent research are from increased NAD+ circulating in the bloodstream, not NR. Sublingual NAD+ or NMN are likely much more efficient methods...
NAD+ is the Transport Molecule Used by the Body...
The benefits noted from supplementation with NR in recent research are from increased NAD+ circulating in...
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport a small quantity of Nicotinamide Mononucleotide (NMN) directly into some cells.
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport...
Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...
Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90...