Research
Senescent Cells: The Double-Edged Sword of Cell...
This paradox makes senescent cells a double-edged sword: necessary for short-term health but harmful in the long run. Because of this, scientists are now exploring new ways to support long-term...
Senescent Cells: The Double-Edged Sword of Cell...
This paradox makes senescent cells a double-edged sword: necessary for short-term health but harmful in the...
Long Term NMN Use Extends Lifespan and Healthsp...
Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male and female mice. Enhanced metabolic health, particularly in male mice. Altered gut microbiome with...
Long Term NMN Use Extends Lifespan and Healthsp...
Key Points Increased median lifespan by 8.5% in female mice. Reduced frailty observed in both male...
Slc12a8 Transporter is Key for Efficacy of NMN ...
Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport through the Slc12a8 transporter.
Slc12a8 Transporter is Key for Efficacy of NMN ...
Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport...
Study Demonstrates Age Reversal through Cellula...
A team of scientists from Harvard Medical School discovered a method to distinguish young cells from old and senescent cells in real time. This allowed them to quickly screen the...
Study Demonstrates Age Reversal through Cellula...
A team of scientists from Harvard Medical School discovered a method to distinguish young cells from...
NR Shows Ability to Promote DNA Repair and Incr...
Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this study were shown to have an effect on lifespan in mice engineered to age...
NR Shows Ability to Promote DNA Repair and Incr...
Nicotinamide Riboside (NR) shown to increase lifespan of mice by 25% Only two compounds in this...
NAD+ Reduces Mutations and Incidence of Skin Ca...
NMN and NR lead to greater increases in NAD+ than NAM It has been well established that the molecules NMN and NR lead to greater increases in NAD+ levels than...
NAD+ Reduces Mutations and Incidence of Skin Ca...
NMN and NR lead to greater increases in NAD+ than NAM It has been well established...
Fisetin Effectively Eliminates Senescent Cells ...
Since immune cells play such a critical role in keeping the population of senescent cells in check, senescent immune cells are a prime target of senolytic drugs. Fisetin has been...
Fisetin Effectively Eliminates Senescent Cells ...
Since immune cells play such a critical role in keeping the population of senescent cells in...
Heart Disease Related to Accumulation of DNA Da...
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...
Heart Disease Related to Accumulation of DNA Da...
As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field of longevity research. In a recent video, titled “Dr David Sinclair – Defeating Ageing...
David Sinclair's Supplement Stack and Longevity...
David Sinclair, a professor at Harvard University is perhaps the foremost expert in the growing field...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark of aging and is a major cause of decreased tissue homeostasis in the old...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark...
Trimethylglycine (TMG) for Restoring Methylatio...
TMG is a critical cofactor in methylation, which occurs in every mammalian cell donating methyl groups. This includes the synthesis of neurotransmitters such as serotonin and dopamine.
Trimethylglycine (TMG) for Restoring Methylatio...
TMG is a critical cofactor in methylation, which occurs in every mammalian cell donating methyl groups....
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation of cells. Its secondary mediator, insulin-like growth factor 1 (IGF-1), is produced in response...
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation...