Research

Study Shows NR Injections Increase Muscle NAD+ ...
NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in muscle NAD+ was observed after 7 days of IV administration of NR. Oral administration...
Study Shows NR Injections Increase Muscle NAD+ ...
NR injections boosted NAD+ levels in skeletal muscle and white adipose tissue. A ~140% increase in...

NMN Human Trial Shows Increased Endurance, NAD+...
Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels are known to decline with age, affecting longevity and age-related health conditions, better known...
NMN Human Trial Shows Increased Endurance, NAD+...
Study set out to determine safety and efficacy of NMN supplementation in 4 groups NAD+ levels...

NAD Precursors Cycle Between Host Tissues and t...
Thus, circulating host NAM enters the gut lumen and is used by the microbiome for both NAD and NA synthesis. Thus, gut microbiota provide an alternative route from NAM to...
NAD Precursors Cycle Between Host Tissues and t...
Thus, circulating host NAM enters the gut lumen and is used by the microbiome for both...

Dogs and Humans Share Same Benefits from NMN Su...
Dog and human NAD+ levels both decline with age Dogs have the same problem as humans in that their NAD+ levels decline with age in various critical organs, such as...
Dogs and Humans Share Same Benefits from NMN Su...
Dog and human NAD+ levels both decline with age Dogs have the same problem as humans...

NMN and Resveratrol Work Synergistically to boo...
A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+ levels in both heart and skeletal muscle tissues in mice. Combination treatments shown to...
NMN and Resveratrol Work Synergistically to boo...
A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+...

NAD+ Reduces Mutations and Incidence of Skin Ca...
NMN and NR lead to greater increases in NAD+ than NAM It has been well established that the molecules NMN and NR lead to greater increases in NAD+ levels than...
NAD+ Reduces Mutations and Incidence of Skin Ca...
NMN and NR lead to greater increases in NAD+ than NAM It has been well established...

NAD+ and the Hallmarks of Aging Series - Part 9...
All species of animals, including the human being, are multicellular organisms (an organism that consists of more than one cell).
NAD+ and the Hallmarks of Aging Series - Part 9...
All species of animals, including the human being, are multicellular organisms (an organism that consists of...

Inhibition of CD38 Increases NAD+ Levels
Inhibition of CD38 Increases NAD+ and Extends Lifespan and Healthspan Two recent studies have found that inhibition of CD38 (with 78c or PCC1) increase NAD+ levels and result in significant...
Inhibition of CD38 Increases NAD+ Levels
Inhibition of CD38 Increases NAD+ and Extends Lifespan and Healthspan Two recent studies have found that...

NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels (right graph). Dr. David Sinclair is a co-founder of...
NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice...

Why Dr. Sinclair takes NMN instead of NR
“NMN makes mice run further. Old mice can run 50% further, because they have better blood flow, better energy. NR at the same dose did not do that. In fact...
Why Dr. Sinclair takes NMN instead of NR
“NMN makes mice run further. Old mice can run 50% further, because they have better blood...

Lower Inflammation to Raise NAD+
Results from hundreds of tests for Intracellular NAD+ levels tell us that those with high inflammation levels (measured by HS-CRP) have less success raising NAD+ levels.Lowering inflammation can help restore...
Lower Inflammation to Raise NAD+
Results from hundreds of tests for Intracellular NAD+ levels tell us that those with high inflammation...

NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark of aging and is a major cause of decreased tissue homeostasis in the old...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark...