Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--Neuroprotective Effects of NAD+ Nasal Spray

Neuroprotective Effects of NAD+ Nasal Spray

3 min

"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to brain tissues, thereby circumventing the hepatic first-pass metabolism and gastric degradation and allowing fast...

3 min

Neuroprotective Effects of NAD+ Nasal Spray

"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to...

article-page-carousel-item--NMN Reduced Cellular Aging and Improved Survivability in Mice

NMN Reduced Cellular Aging and Improved Su...

4 min

This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation, mitochondrial function, and survival in mice.

4 min

NMN Reduced Cellular Aging and Improved Surviva...

This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation,...

article-page-carousel-item--Higher NMN levels in breast milk linked to better neurodevelopment in offspring

Higher NMN levels in breast milk linked to...

4 min

โ€œNMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the first time, a positive relationship between NMN concentrations in breast milk and the neurodevelopmental...

4 min

Higher NMN levels in breast milk linked to bett...

โ€œNMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the...

article-page-carousel-item--NMN Enhances Spinal Cord Injury Recovery in Mice

NMN Enhances Spinal Cord Injury Recovery i...

4 min

โ€œNMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways related to neurological diseases.โ€

4 min

NMN Enhances Spinal Cord Injury Recovery in Mice

โ€œNMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways...

article-page-carousel-item--High-Dose NR is Safe & Does Not Deplete Methyl Pools in PD Trial

High-Dose NR is Safe & Does Not Deplete Me...

4 min

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in patients with Parkinsonโ€™s Disease (PD).

4 min

High-Dose NR is Safe & Does Not Deplete Methyl ...

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in...

article-page-carousel-item--Clinical Trial Fails to Find Significant Benefit of NR in Adults with MCI

Clinical Trial Fails to Find Significant B...

5 min

This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI and effectively increased blood levels of NAD+.

5 min

Clinical Trial Fails to Find Significant Benefi...

This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI...

article-page-carousel-item--Deep Sleep May Protect Against Dementia

Deep Sleep May Protect Against Dementia

2 min

โ€œThese data from a community-based sample demonstrate that SWS percentage declines over time in adults 60 years and older and that greater declines are associated with the risk of future...

2 min

Deep Sleep May Protect Against Dementia

โ€œThese data from a community-based sample demonstrate that SWS percentage declines over time in adults 60...

article-page-carousel-item--Palmitoylethanolamide (P.E.A.) Reduces Inflammation and Anxiety in Obese Mice

Palmitoylethanolamide (P.E.A.) Reduces Inf...

4 min

This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation.ย โ€œAs our data demonstrated, the blunted synthesis of pro-inflammatory cytokines by PEA can stop this vicious cycle among...

4 min

Palmitoylethanolamide (P.E.A.) Reduces Inflamma...

This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation.ย โ€œAs our data demonstrated,...

article-page-carousel-item--Study Finds NR Reaches the Brain & Improves Neuron Function

Study Finds NR Reaches the Brain & Improve...

2 min

โ€œBut until now, it was unknown whether NR reached targeted organs like the brain to have a real therapeutic effect,โ€ according to Christopher Martens, one of the key researchers in...

2 min

Study Finds NR Reaches the Brain & Improves Neu...

โ€œBut until now, it was unknown whether NR reached targeted organs like the brain to have...

Increasing NMN Transporter in the Brain Re...

2 min

Doubling Slc128a Dramatically Improved Muscle Strength and Endurance Itโ€™s known that NMN transporters like Slc128a help to maintain NAD+ levels as we age. This caused researchers to speculate what may...

2 min

Increasing NMN Transporter in the Brain Reduces...

Doubling Slc128a Dramatically Improved Muscle Strength and Endurance Itโ€™s known that NMN transporters like Slc128a help...

article-page-carousel-item--Newly Found Benefits of Resveratrol in Health and Anti-aging

Newly Found Benefits of Resveratrol in Hea...

5 min

Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body's own self-repair proteins, called sirtuins. When sirtuins are activated,...

5 min

Newly Found Benefits of Resveratrol in Health a...

Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance...

article-page-carousel-item--Increased NAD+ in Bloodstream of Nursing Mice Results in Healthier, Stronger, Smarter Offspring

Increased NAD+ in Bloodstream of Nursing M...

4 min

These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...

4 min

Increased NAD+ in Bloodstream of Nursing Mice R...

These improvements in health and behavior persisted for the length of the study, which was 90...