Research
NAD+ and the Hallmarks of Aging Series - Part 6...
These findings suggest that a conserved pathway may operate in mammals during calorie restriction involving the activation of SIRT1 and increased NAD+ that triggers an increase in mitochondrial activity, which...
NAD+ and the Hallmarks of Aging Series - Part 6...
These findings suggest that a conserved pathway may operate in mammals during calorie restriction involving the...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the opposite of what you are trying to accomplish by taking NAD+ boosters. The body...
Why Too Much NMN or NR is Bad
High levels of NAM can have many negative effects such as inhibiting sirtuins, which is the...
Reduced Nicotinamide Mononucleotide - A Tale of...
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are both well-known NAD+ precursors that can effectively increase NAD+ levels across multiple tissues. They are very similar to each other. In fact,...
Reduced Nicotinamide Mononucleotide - A Tale of...
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are both well-known NAD+ precursors that can effectively increase...
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation of cells. Its secondary mediator, insulin-like growth factor 1 (IGF-1), is produced in response...
NAD+ and the Hallmarks of Aging Series - Part 5...
Growth Hormone and Insulin Growth hormone is a well-known hormone that promotes the growth and proliferation...
Bacteria in Gastrointestional Tract Metabolize ...
Several experiments were completed that all measured NAD+ metabolites in the Gastrointestinal Tract (GIT) and Liver, 4 hours after a single dose of either 50mg/kg or 500 mg/kg by oral...
Bacteria in Gastrointestional Tract Metabolize ...
Several experiments were completed that all measured NAD+ metabolites in the Gastrointestinal Tract (GIT) and Liver,...
CD73 utilization shows importance of NMN to res...
Like prior studies (1), they found that this transport method did not impede NMN from entering cells, as NR and NMN performed equally at restoring NAD+. They also determined that...
CD73 utilization shows importance of NMN to res...
Like prior studies (1), they found that this transport method did not impede NMN from entering...
How NAD+ Boosts ATP and What it Means for Healt...
Declining ATP as we age Adenosine triphosphate (ATP) is the main biological fuel used by our body. It provides every cell with energy for the essential processes such as muscle...
How NAD+ Boosts ATP and What it Means for Healt...
Declining ATP as we age Adenosine triphosphate (ATP) is the main biological fuel used by our...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of 3 μmole/min all exogenously infused NAD+ was rapidly and completely removed from the plasma...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of...
NAD+ is the Transport Molecule Used by the Body...
The benefits noted from supplementation with NR in recent research are from increased NAD+ circulating in the bloodstream, not NR. Sublingual NAD+ or NMN are likely much more efficient methods...
NAD+ is the Transport Molecule Used by the Body...
The benefits noted from supplementation with NR in recent research are from increased NAD+ circulating in...
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport a small quantity of Nicotinamide Mononucleotide (NMN) directly into some cells.
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport...
Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...
Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90...