Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--Bacteria in Gastrointestional Tract Metabolize NMN and Impact NAD+ Metabolome

Bacteria in Gastrointestional Tract Metabo...

5 min

Several experiments were completed that all measured NAD+ metabolites in the Gastrointestinal Tract (GIT) and Liver, 4 hours after a single dose of either 50mg/kg or 500 mg/kg by oral...

5 min

Bacteria in Gastrointestional Tract Metabolize ...

Several experiments were completed that all measured NAD+ metabolites in the Gastrointestinal Tract (GIT) and Liver,...

article-page-carousel-item--CD73 utilization shows importance of NMN to restore NAD+

CD73 utilization shows importance of NMN t...

7 min

Like prior studies (1), they found that this transport method did not impede NMN from entering cells, as NR and NMN performed equally at restoring NAD+. They also determined that...

7 min

CD73 utilization shows importance of NMN to res...

Like prior studies (1), they found that this transport method did not impede NMN from entering...

article-page-carousel-item--1st NMN Human Study Demonstrates Safety and Faster Utilization than NR

1st NMN Human Study Demonstrates Safety an...

4 min

The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be...

4 min

1st NMN Human Study Demonstrates Safety and Fas...

The single oral administration of NMN was safe and effectively metabolized in healthy men without causing...

article-page-carousel-item--NAD+ IV increases NAD+ levels in blood plasma 400% in humans

NAD+ IV increases NAD+ levels in blood pla...

6 min

In summary, this study revealed for the first time that: (a) at a flow rate of 3 μmole/min all exogenously infused NAD+ was rapidly and completely removed from the plasma...

6 min

NAD+ IV increases NAD+ levels in blood plasma 4...

In summary, this study revealed for the first time that: (a) at a flow rate of...

article-page-carousel-item--Increased NAD+ in Bloodstream of Nursing Mice Results in Healthier, Stronger, Smarter Offspring

Increased NAD+ in Bloodstream of Nursing M...

4 min

These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...

4 min

Increased NAD+ in Bloodstream of Nursing Mice R...

These improvements in health and behavior persisted for the length of the study, which was 90...

article-page-carousel-item--Scientists discover SLC12a8 pathway used by NMN to restore NAD+ levels

Scientists discover SLC12a8 pathway used b...

10 min

More details about the research Slc12a8 in the small intestine is important for transporting NMN from the gut into the circulation, affecting NAD+ levels in the small intestine and the...

10 min

Scientists discover SLC12a8 pathway used by NMN...

More details about the research Slc12a8 in the small intestine is important for transporting NMN from...

article-page-carousel-item--NAD+ Supplements Regulate Energy Metabolism via the Hypothalamus

NAD+ Supplements Regulate Energy Metabolis...

8 min

This study shows that administration of 1 mg/kg of LABELED NAD+ crosses the blood brain barrier to enter the hypothalamus INTACT, increases NAD+ levels, reduces hunger and weight gain, and...

8 min

NAD+ Supplements Regulate Energy Metabolism via...

This study shows that administration of 1 mg/kg of LABELED NAD+ crosses the blood brain barrier...

article-page-carousel-item--Exogenous NAD+ Increases Metabolism

Exogenous NAD+ Increases Metabolism

2 min

In a study published in 2018, scientists gave obese mice 1 mg/kg of NAD+ by inter peritoneal injection for 4 weeks, which restored NAD+ levels in the hypothalamus to normal...

2 min

Exogenous NAD+ Increases Metabolism

In a study published in 2018, scientists gave obese mice 1 mg/kg of NAD+ by inter...