Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--A Novel NAD+ Precursor (NRH) Improves Glucose and Fat Metabolism in Obese Mice

A Novel NAD+ Precursor (NRH) Improves Gluc...

7 min

“To our knowledge, this is the first report showing that NRH can reach multiple tissues intact and provide a broad spectrum of effects through potent NAD+ enhancement and subsequent SIRT...

7 min

A Novel NAD+ Precursor (NRH) Improves Glucose a...

“To our knowledge, this is the first report showing that NRH can reach multiple tissues intact...

article-page-carousel-item--Increased NAD+ Turnover, Minor Decline in Levels in COVID-19 Patients

Increased NAD+ Turnover, Minor Decline in ...

4 min

“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation, supporting the rationale for NAD+ augmentation to attenuate disease severity.”

4 min

Increased NAD+ Turnover, Minor Decline in Level...

“NAD+ turnover is substantially increased with upregulation of genes involved in both NAD+ biosynthesis and degradation,...

article-page-carousel-item--NR IV Exhibits Faster NAD+ Rise and Better Tolerability in Humans

NR IV Exhibits Faster NAD+ Rise and Better...

5 min

“In comparison to NAD+ IV, NR IV was infused faster, and the infusion experience was more tolerable.”

5 min

NR IV Exhibits Faster NAD+ Rise and Better Tole...

“In comparison to NAD+ IV, NR IV was infused faster, and the infusion experience was more...

article-page-carousel-item--NAD+ Nanoparticle Injection Decreased Blood Vessel Damage In Rats

NAD+ Nanoparticle Injection Decreased Bloo...

3 min

A new study found injection of NAD+ using a novel liposome-like nano-particle carrier reduced overgrowth of smooth muscle cells and improved blood vessel healing in rats with narrowed arteries.

3 min

NAD+ Nanoparticle Injection Decreased Blood Ves...

A new study found injection of NAD+ using a novel liposome-like nano-particle carrier reduced overgrowth of...

article-page-carousel-item--Neuroprotective Effects of NAD+ Nasal Spray

Neuroprotective Effects of NAD+ Nasal Spray

3 min

"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to brain tissues, thereby circumventing the hepatic first-pass metabolism and gastric degradation and allowing fast...

3 min

Neuroprotective Effects of NAD+ Nasal Spray

"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to...

article-page-carousel-item--NAD+ Injections Guard Against Heart Failure in Rats and Beagles

NAD+ Injections Guard Against Heart Failur...

4 min

“This study, involving rat and beagle MI-induced HF models, indicated that NAD+ significantly improves myocardial hypertrophy and cardiac function, inhibits myocardial fibrosis, and reduces the myocardial infarction rate.”

4 min

NAD+ Injections Guard Against Heart Failure in ...

“This study, involving rat and beagle MI-induced HF models, indicated that NAD+ significantly improves myocardial hypertrophy...

article-page-carousel-item--Extracellular NAD+ Suppresses Inflammatory Response

Extracellular NAD+ Suppresses Inflammatory...

3 min

A recent literature review explored the impact of extracellular NAD+ on the inflammatory response.

3 min

Extracellular NAD+ Suppresses Inflammatory Resp...

A recent literature review explored the impact of extracellular NAD+ on the inflammatory response.

article-page-carousel-item--NAD+ IV Infusion Enhanced Recovery in Heart Failure Patients

NAD+ IV Infusion Enhanced Recovery in Hear...

3 min

This study evaluated the effects of NAD+ injections in patients with heart failure.

3 min

NAD+ IV Infusion Enhanced Recovery in Heart Fai...

This study evaluated the effects of NAD+ injections in patients with heart failure.

article-page-carousel-item--High-Dose NR is Safe & Does Not Deplete Methyl Pools in PD Trial

High-Dose NR is Safe & Does Not Deplete Me...

4 min

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in patients with Parkinson’s Disease (PD).

4 min

High-Dose NR is Safe & Does Not Deplete Methyl ...

This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in...

article-page-carousel-item--Efficacy and Safety of NAD+ Precursors in Clinical Trials

Efficacy and Safety of NAD+ Precursors in ...

4 min

A recent systematic review evaluated ten studies with NAD+ precursors for efficacy and safety.

4 min

Efficacy and Safety of NAD+ Precursors in Clini...

A recent systematic review evaluated ten studies with NAD+ precursors for efficacy and safety.

article-page-carousel-item--NR Regulates the Cardiac Internal Clock of Aged Mice

NR Regulates the Cardiac Internal Clock of...

2 min

Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's time to sleep, wake up, eat, and digest. This study evaluated the effects of...

2 min

NR Regulates the Cardiac Internal Clock of Aged...

Circadian rhythm is your body's internal clock that permits anticipation of daily patterns, regulating when it's...

article-page-carousel-item--Novel Delivery System Improves NMN Absorption in Mice

Novel Delivery System Improves NMN Absorpt...

4 min

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

4 min

Novel Delivery System Improves NMN Absorption i...

“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN,...