Research
Nicotinamide Riboside Shows Promise in Treating...
“Depletion of nicotinamide adenine dinucleotide (NAD)+ has been reported in patients with WS, suggesting a key role in the pathogenesis of WS.” Key Points No serious adverse effects reported NR...
Nicotinamide Riboside Shows Promise in Treating...
“Depletion of nicotinamide adenine dinucleotide (NAD)+ has been reported in patients with WS, suggesting a key...
From Leaf to Cell: Understanding EGCG's Impact ...
Antioxidant protection: EGCG exhibits potent free radical scavenging capabilities, protecting cellular structures from oxidative damage and supporting DNA integrity. Cellular health support: EGCG promotes optimal cellular function and helps maintain...
From Leaf to Cell: Understanding EGCG's Impact ...
Antioxidant protection: EGCG exhibits potent free radical scavenging capabilities, protecting cellular structures from oxidative damage and...
Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have been leading choices for raising NAD+ levels. Their popularity stems from the limitations of...
Oral NAD+: Revisiting Assumptions about Efficacy
Image source: Alegre, et al., 2025 For years, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) have...
Fighting Immunosenescence with Quercetin
The Natural Enemy of Immunosenescence Aging brings significant shifts to the immune system, collectively referred to as immunosenescence. These changes include reduced immune surveillance, diminished efficiency in responding to infections,...
Fighting Immunosenescence with Quercetin
The Natural Enemy of Immunosenescence Aging brings significant shifts to the immune system, collectively referred to...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects “The aim of this study was to confirm the safety of our manufactured NMN...
Safety Trial Favors High Dose NMN
Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...
NR Improved Brain and Blood Vessel Health in Ad...
Key Points Blood vessel function improved after 4 weeks of NR supplementation Brain blood flow increased in areas linked to memory and decision-making Participants showed modest gains in cognitive tests,...
NR Improved Brain and Blood Vessel Health in Ad...
Key Points Blood vessel function improved after 4 weeks of NR supplementation Brain blood flow increased...
Safety of IV Nicotinamide Riboside at Different...
Key Points IV NR was well tolerated at doses up to 450 mg/kg High doses (600 mg/kg) caused negative effects, including cardiovascular, liver, and kidney damage Increasing Doses of IV...
Safety of IV Nicotinamide Riboside at Different...
Key Points IV NR was well tolerated at doses up to 450 mg/kg High doses (600...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...
NAD+ as a Multi-Target Therapy for Neurodegener...
Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers, and...
Mouse Study Shows Organ-Specific Effects of NAD...
Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers...
NMN Reversed Age-Related Metabolic Dysfunction ...
Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced The metabolism of inflammatory fats was altered Study Overview Aging was modeled in mice...
NMN Reversed Age-Related Metabolic Dysfunction ...
Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced...
NR Boosts Fat-Burning Activity in Obese Mice
What is Brown Fat and Why is it Important? Brown fat, or brown adipose tissue (BAT), is a special type of body fat that burns energy to produce heat -...
NR Boosts Fat-Burning Activity in Obese Mice
What is Brown Fat and Why is it Important? Brown fat, or brown adipose tissue (BAT),...
Efficacy of Liposomal Delivery Systems in Nutra...
Liposomal Delivery: What It Is and Why It Matters When it comes to supplements, taking them is one thing, but being able to actually absorb and use them is another....
Efficacy of Liposomal Delivery Systems in Nutra...
Liposomal Delivery: What It Is and Why It Matters When it comes to supplements, taking them...