Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--NMN Extended Lifespan in Fast-Aging Mice

NMN Extended Lifespan in Fast-Aging Mice

3 min

β€œWe showed that NMN consistently extended the healthy and median lifespan of Zmpste24-/- and improved the Zmpste24-/- ageing phenotype."

3 min

NMN Extended Lifespan in Fast-Aging Mice

β€œWe showed that NMN consistently extended the healthy and median lifespan of Zmpste24-/- and improved the...

article-page-carousel-item--NMN Protects Skin and Improves Prognosis in Psoriatic Mice

NMN Protects Skin and Improves Prognosis i...

4 min

β€œWe demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and improve therapeutic prognoses by activating the SIRT1 pathway.”

4 min

NMN Protects Skin and Improves Prognosis in Pso...

β€œWe demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and...

article-page-carousel-item--NMN Reduced Cellular Aging and Improved Survivability in Mice

NMN Reduced Cellular Aging and Improved Su...

4 min

This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation, mitochondrial function, and survival in mice.

4 min

NMN Reduced Cellular Aging and Improved Surviva...

This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation,...

article-page-carousel-item--Higher NMN levels in breast milk linked to better neurodevelopment in offspring

Higher NMN levels in breast milk linked to...

4 min

β€œNMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the first time, a positive relationship between NMN concentrations in breast milk and the neurodevelopmental...

4 min

Higher NMN levels in breast milk linked to bett...

β€œNMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the...

article-page-carousel-item--Enhanced NMN Detection Validates Slc12a8-Dependent Uptake

Enhanced NMN Detection Validates Slc12a8-D...

5 min

β€œWe have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed quick, direct NMN uptake into blood circulation and cells.”

5 min

Enhanced NMN Detection Validates Slc12a8-Depend...

β€œWe have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed...

article-page-carousel-item--NMN Enhances Spinal Cord Injury Recovery in Mice

NMN Enhances Spinal Cord Injury Recovery i...

4 min

β€œNMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways related to neurological diseases.”

4 min

NMN Enhances Spinal Cord Injury Recovery in Mice

β€œNMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways...

article-page-carousel-item--NMN Improves Airway Function in Asthmatic Mice

NMN Improves Airway Function in Asthmatic ...

3 min

This study found that injection of NMN protected mice from asthma-induced inflammation, mucus production, and lung barrier disruption.

3 min

NMN Improves Airway Function in Asthmatic Mice

This study found that injection of NMN protected mice from asthma-induced inflammation, mucus production, and lung...

article-page-carousel-item--Slc12a8 Transporter is Key for Efficacy of NMN in Septic Mice

Slc12a8 Transporter is Key for Efficacy of...

6 min

Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport through the Slc12a8 transporter.

6 min

Slc12a8 Transporter is Key for Efficacy of NMN ...

Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport...

article-page-carousel-item--Novel Preparation and Analysis of Liposomal NMN

Novel Preparation and Analysis of Liposoma...

3 min

The study developed a novel microfluidic approach to co-encapsulate NMN and an anticancer drug, honokiol (HNK), in liposomes and established a new HPLC method for NMN encapsulation quantification.

3 min

Novel Preparation and Analysis of Liposomal NMN

The study developed a novel microfluidic approach to co-encapsulate NMN and an anticancer drug, honokiol (HNK),...

article-page-carousel-item--NMN Enhanced HIV-1 Therapy in Mice

NMN Enhanced HIV-1 Therapy in Mice

2 min

β€œResults from the humanized mouse study demonstrated that NMN treatment could improve the therapeutic effect of cART in vivo on reconstituting CD4+ T cells and improving CD4/CD8 ratio significantly over...

2 min

NMN Enhanced HIV-1 Therapy in Mice

β€œResults from the humanized mouse study demonstrated that NMN treatment could improve the therapeutic effect of...

article-page-carousel-item--Confirmation NMN enters some cells directly

Confirmation NMN enters some cells directly

2 min

A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN uptake and metabolism in cells.Β  Β 

2 min

Confirmation NMN enters some cells directly

A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN...

article-page-carousel-item--Novel Delivery System Improves NMN Absorption in Mice

Novel Delivery System Improves NMN Absorpt...

4 min

β€œUpon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”

4 min

Novel Delivery System Improves NMN Absorption i...

β€œUpon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN,...