Scientific Evidence Library
NMN Extended Lifespan in Fast-Aging Mice
“We showed that NMN consistently extended the healthy and median lifespan of Zmpste24-/- and improved the Zmpste24-/- ageing phenotype."
NMN Extended Lifespan in Fast-Aging Mice
“We showed that NMN consistently extended the healthy and median lifespan of Zmpste24-/- and improved the...
NMN Protects Skin and Improves Prognosis in Pso...
“We demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and improve therapeutic prognoses by activating the SIRT1 pathway.”
NMN Protects Skin and Improves Prognosis in Pso...
“We demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and...
NMN Reduced Cellular Aging and Improved Surviva...
This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation, mitochondrial function, and survival in mice.
NMN Reduced Cellular Aging and Improved Surviva...
This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation,...
Higher NMN levels in breast milk linked to bett...
“NMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the first time, a positive relationship between NMN concentrations in breast milk and the neurodevelopmental...
Higher NMN levels in breast milk linked to bett...
“NMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the...
Enhanced NMN Detection Validates Slc12a8-Depend...
“We have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed quick, direct NMN uptake into blood circulation and cells.”
Enhanced NMN Detection Validates Slc12a8-Depend...
“We have demonstrated that this methodology can accurately quantitate NMN levels in mouse plasma and confirmed...
NMN Enhances Spinal Cord Injury Recovery in Mice
“NMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways related to neurological diseases.”
NMN Enhances Spinal Cord Injury Recovery in Mice
“NMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways...
NMN Improves Airway Function in Asthmatic Mice
This study found that injection of NMN protected mice from asthma-induced inflammation, mucus production, and lung barrier disruption.
NMN Improves Airway Function in Asthmatic Mice
This study found that injection of NMN protected mice from asthma-induced inflammation, mucus production, and lung...
Slc12a8 Transporter is Key for Efficacy of NMN ...
Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport through the Slc12a8 transporter.
Slc12a8 Transporter is Key for Efficacy of NMN ...
Sepsis-associated disruption of the NRK1/2 pathway for NAD+ synthesis emphasized the critical role of NMN transport...
Novel Preparation and Analysis of Liposomal NMN
The study developed a novel microfluidic approach to co-encapsulate NMN and an anticancer drug, honokiol (HNK), in liposomes and established a new HPLC method for NMN encapsulation quantification.
Novel Preparation and Analysis of Liposomal NMN
The study developed a novel microfluidic approach to co-encapsulate NMN and an anticancer drug, honokiol (HNK),...
NMN Enhanced HIV-1 Therapy in Mice
“Results from the humanized mouse study demonstrated that NMN treatment could improve the therapeutic effect of cART in vivo on reconstituting CD4+ T cells and improving CD4/CD8 ratio significantly over...
NMN Enhanced HIV-1 Therapy in Mice
“Results from the humanized mouse study demonstrated that NMN treatment could improve the therapeutic effect of...
Confirmation NMN enters some cells directly
A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN uptake and metabolism in cells.
Confirmation NMN enters some cells directly
A study reported new insights into NAD+ precursor dynamics using a novel method to follow NMN...
Novel Delivery System Improves NMN Absorption i...
“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN, leading to elevated plasma levels of both NAD+ and its precursor, NR.”
Novel Delivery System Improves NMN Absorption i...
“Upon oral administration, NMN–HAP nanoparticles demonstrated prolonged circulation time and enhanced bioavailability compared with free NMN,...