Scientific Evidence Library

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Scientific Evidence Library

article-page-carousel-item--Emerging Strategies, Applications, and Challenges of Targeting NAD⁺ in the Clinic: A Review

Emerging Strategies, Applications, and Cha...

11 min

Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a master regulator of health, supporting DNA repair, epigenetic programming, immune responses, and mitochondrial function....

11 min

Emerging Strategies, Applications, and Challeng...

Once regarded as a simple coenzyme required for energy production, NAD⁺ is now recognized as a...

article-page-carousel-item--Mouse Study Shows Organ-Specific Effects of NAD+ Modulation on Aging

Mouse Study Shows Organ-Specific Effects o...

3 min

Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers, and...

3 min

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers...

article-page-carousel-item--NMN Protects Mitochondria and Reduces Heart Injury in Septic Mice

NMN Protects Mitochondria and Reduces Hear...

4 min

This study demonstrated that NMN protected heart function in septic mice by reducing mitochondrial free radical production and correcting abnormal protein modifications in mitochondria.

4 min

NMN Protects Mitochondria and Reduces Heart Inj...

This study demonstrated that NMN protected heart function in septic mice by reducing mitochondrial free radical...

article-page-carousel-item--NMN Enhanced Mitochondrial Stress Response and Improved Cognition in an Alzheimer’s Mouse Model

NMN Enhanced Mitochondrial Stress Response...

6 min

β€œWe combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by which NAD+-boosting agent nicotinamide mononucleotide (NMN) regulates MSR in AD models.”

6 min

NMN Enhanced Mitochondrial Stress Response and ...

β€œWe combined cell biology, molecular biology, and pharmacological approaches to unravel a novel molecular pathway by...

article-page-carousel-item--Liposomal Glutathione Reduced Oxidative Stress and Improved Immune Function in Humans

Liposomal Glutathione Reduced Oxidative St...

4 min

Collectively, these preliminary findings support the effectiveness of daily liposomal GSH administration at elevating stores of GSH and impacting immune function and levels of oxidative stress.

4 min

Liposomal Glutathione Reduced Oxidative Stress ...

Collectively, these preliminary findings support the effectiveness of daily liposomal GSH administration at elevating stores of...

article-page-carousel-item--NMN Enhances Cellular Protection and Cognitive Function in Alzheimer’s Disease Mice

NMN Enhances Cellular Protection and Cogni...

5 min

Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory Reduced neuronal injury Promoted clearance of abnormal tau protein Activated autophagy Enhanced antioxidant defense...

5 min

NMN Enhances Cellular Protection and Cognitive ...

Key Points Treatment with NMN showed several benefits for mice with AD: Enhanced cognition and memory...

article-page-carousel-item--NMN Protects Skin and Improves Prognosis in Psoriatic Mice

NMN Protects Skin and Improves Prognosis i...

4 min

β€œWe demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and improve therapeutic prognoses by activating the SIRT1 pathway.”

4 min

NMN Protects Skin and Improves Prognosis in Pso...

β€œWe demonstrated that NMN could ameliorate psoriasis-like symptoms and inflammation in an IMQ-stimulated mouse model and...

article-page-carousel-item--Study Shows NMN Protects Against Lung Damage in Mice

Study Shows NMN Protects Against Lung Dama...

5 min

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure and protected against pulmonary fibrosis in mice.

5 min

Study Shows NMN Protects Against Lung Damage in...

Oral administration of NMN (500 mg/kg) effectively preserved NAD+ tissue and plasma levels during PM exposure...

article-page-carousel-item--Study Finds Liposomal Berberine Improves Glucose, Lipids, and Inflammation in Rats

Study Finds Liposomal Berberine Improves G...

5 min

β€œIn an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme...

5 min

Study Finds Liposomal Berberine Improves Glucos...

β€œIn an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited...

article-page-carousel-item--Heart Disease Related to Accumulation of DNA Damage and Oxidative Stress

Heart Disease Related to Accumulation of D...

2 min

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A recent study looking at the DNA in numerous individual heart cells tells the story...

2 min

Heart Disease Related to Accumulation of DNA Da...

As we age, the risk for clogged arteries, brittle blood vessels, and heart failure increase. A...