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Serving size 1 capsule

90 Capsules Allergen-Free

褪黑激素（脂质体）

Name: 褪黑激素（脂质体）90 粒
Brand: Renue Store
SKU: 850055685048
Price: 36.75 AUD
Availability: InStock

天然激素帮助睡眠

$36.75 AUD

$36.75 AUD ~~$45.95~~

结账时计算的运费。

LIPO 褪黑激素采用我们专有的粉末状脂质体，由天然磷脂分子制成，可保护其免受消化酶的侵害，并将其带入血液进行有针对性的全身输送。

我们的复合产品中也含有 LIPO 褪黑激素，恢复 PM。

产品多属性

Serving size 1 capsule

90 Capsules Allergen-Free

LIPO Melatonin Details

LIPO Melatonin™ promotes high-quality sleep and balances your “body clock.” Benefits may include improvement of sleep onset, sleep pattern and a decrease in cortisol levels.

Offering an advanced liposomal source of the natural hormone—N-acetyl-5-methoxytryptamine—LIPO Melatonin™ is expertly designed to overcome low absorption issues.

Balance Cortisol Levels

Melatonin is mainly known for its ability to regulate the sleep-wake cycle (circadian rhythm or chronobiology) via its release from the pineal gland. Studies demonstrate that melatonin decreases sleep onset latency, increases total sleep time and improves overall sleep quality. 1

In addition to improving sleep, melatonin is also involved in managing immune function, blood pressure and cortisol levels. 2

Only 15% Absorption in Standard Melatonin Supplements

Oral melatonin has an absolute bioavailability of about 15 percent. So, if you take a 4 mg melatonin pill, your body is only absorbing around 0.6 mg. 3

Our encapsulation process in liposomes protects melatonin from premature degradation while enhancing its intestinal absorption.

The absorption of non-liposomal oral melatonin is minimal due to high first-pass clearance in the liver and low absorption in the gastrointestinal tract. 4

Liposomes extend the time a supplement is available in the bloodstream, but the peak availability is between 2 and 4 hours, which is while you are sleeping.

However, some is absorbed well before the 2 hours and actually may work faster than standard Melatonin.

This study found Liposomal Melatonin decreased the time to sleep (Sleep latency – SL). from 18 minutes to 10 minutes.

“A significant difference in SL was observed (10.8 ± 5 vs. 18.1 ± 13.4 min, p-value = 0.002)… Our study confirmed the efficacy and safety of melatonin administration in sleep induction. Nonetheless, liposomal melatonin presents a greater bioavailability, ensuring a faster effect and allowing lower dosages.”

查看完整详细信息

LIPO Melatonin™ 可促进高质量睡眠并平衡您的“生物钟”。其益处包括改善入睡时间、改善睡眠模式和降低皮质醇水平。

LIPO Melatonin™ 提供先进的天然激素脂质体来源——N-乙酰-5-甲氧基色胺，经过专业设计，可克服吸收率低的问题。

平衡皮质醇水平

褪黑激素主要因其通过松果体释放来调节睡眠-觉醒周期（昼夜节律或时间生物学）的能力而闻名。研究表明，褪黑激素可减少入睡潜伏期，增加总睡眠时间并改善整体睡眠质量。1

除了改善睡眠之外，褪黑激素还参与管理免疫功能、血压和皮质醇水平。2

标准褪黑激素补充剂的吸收率仅为 15%

口服褪黑激素的绝对生物利用度约为 15%。因此，如果您服用 4 毫克褪黑激素药丸，您的身体只会吸收约 0.6 毫克。3

我们的脂质体封装工艺可防止褪黑激素过早降解，同时增强其肠道吸收。

非脂质体口服褪黑激素的吸收率极低，这是因为其在肝脏中的首过清除率高，而在胃肠道中的吸收率低。4

脂质体延长了补充剂在血液中的作用时间，但峰值有效性是在 2 至 4 小时之间，也就是在您睡觉时。

然而，有些在 2 小时之前就被吸收了，实际上可能比标准褪黑激素起效更快。

这项研究发现脂质体褪黑激素可缩短睡眠时间（睡眠潜伏期 - SL）。从 18 分钟缩短到 10 分钟。

“观察到 SL 的显著差异（10.8 ± 5 分钟 vs. 18.1 ± 13.4 分钟，p 值 = 0.002）……我们的研究证实了褪黑激素在睡眠诱导中的有效性和安全性。尽管如此，脂质体褪黑激素具有更高的生物利用度，确保更快的效果并允许更低的剂量。”

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Purest Ingredients

All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

Advanced Testing

We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

Certified Labs

Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

Strength and Purity Certification Gold Standard Testing Melatonin Report

常见问题

What are the benefits of liposomal delivery? Are liposomes really better?

When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

What are the liquid and powdered liposome differences in bioavailability and stability?

Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

What's the difference between Liposomal vs. Delayed & Extended Release Caps?

Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

Are any of your liposomal products heat-sensitive?

The liposomal powder capsule products are not heat sensitive.

The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.