Research

Fighting Immunosenescence with Quercetin

The Natural Enemy of Immunosenescence Aging brings significant shifts to the immune system, collectively referred to as immunosenescence. These changes include reduced immune surveillance, diminished efficiency in responding to infections,...

Fighting Immunosenescence with Quercetin

The Natural Enemy of Immunosenescence Aging brings significant shifts to the immune system, collectively referred to...

article-page-carousel-item--Safety Trial Favors High Dose NMN

Safety Trial Favors High Dose NMN

Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects “The aim of this study was to confirm the safety of our manufactured NMN...

Safety Trial Favors High Dose NMN

Key Points No adverse effects observed NAD+ levels increased significantly Overdose levels had no side effects...

article-page-carousel-item--NR Improved Brain and Blood Vessel Health in Adults with PAD

NR Improved Brain and Blood Vessel Health in Ad...

Key Points Blood vessel function improved after 4 weeks of NR supplementation Brain blood flow increased in areas linked to memory and decision-making Participants showed modest gains in cognitive tests,...

NR Improved Brain and Blood Vessel Health in Ad...

Key Points Blood vessel function improved after 4 weeks of NR supplementation Brain blood flow increased...

article-page-carousel-item--Safety of IV Nicotinamide Riboside at Different Doses in Rats

Safety of IV Nicotinamide Riboside at Different...

Key Points IV NR was well tolerated at doses up to 450 mg/kg High doses (600 mg/kg) caused negative effects, including cardiovascular, liver, and kidney damage Increasing Doses of IV...

Safety of IV Nicotinamide Riboside at Different...

Key Points IV NR was well tolerated at doses up to 450 mg/kg High doses (600...

article-page-carousel-item--NAD+ as a Multi-Target Therapy for Neurodegenerative Diseases: A Review of the Evidence

NAD+ as a Multi-Target Therapy for Neurodegener...

Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic potential Early human trials indicate promising clinical benefits Brain delivery and individual response differences...

NAD+ as a Multi-Target Therapy for Neurodegener...

Key Points NAD+ decline is tied to key drivers of NDDs Animal studies show strong therapeutic...

article-page-carousel-item--Mouse Study Shows Organ-Specific Effects of NAD+ Modulation on Aging

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers in older mice Heart & Brain: PnCA reduced NAD+ levels, worsened aging markers, and...

Mouse Study Shows Organ-Specific Effects of NAD...

Key Points: Liver & Kidneys: PnCA increased NAD+ levels, improved mitochondrial function, and delayed aging markers...

article-page-carousel-item--NMN Reversed Age-Related Metabolic Dysfunction by Regulating Inflammation and Fat Metabolism

NMN Reversed Age-Related Metabolic Dysfunction ...

Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced The metabolism of inflammatory fats was altered  Study Overview Aging was modeled in mice...

NMN Reversed Age-Related Metabolic Dysfunction ...

Key Points NMN reduced blood glucose and cholesterol Markers of oxidative stress and inflammation were reduced...

article-page-carousel-item--NR Boosts Fat-Burning Activity in Obese Mice

NR Boosts Fat-Burning Activity in Obese Mice

What is Brown Fat and Why is it Important? Brown fat, or brown adipose tissue (BAT), is a special type of body fat that burns energy to produce heat -...

NR Boosts Fat-Burning Activity in Obese Mice

What is Brown Fat and Why is it Important? Brown fat, or brown adipose tissue (BAT),...

article-page-carousel-item--Efficacy of Liposomal Delivery Systems in Nutraceuticals

Efficacy of Liposomal Delivery Systems in Nutra...

Liposomal Delivery: What It Is and Why It Matters When it comes to supplements, taking them is one thing, but being able to actually absorb and use them is another....

Efficacy of Liposomal Delivery Systems in Nutra...

Liposomal Delivery: What It Is and Why It Matters When it comes to supplements, taking them...

article-page-carousel-item--Navigating Hormonal Transitions: Women’s Health, Perimenopause, and the Path to Resilience

Navigating Hormonal Transitions: Women’s Health...

Understanding Hormonal Shifts During perimenopause and menopause, your body goes through a bit of a hormonal roller coaster, especially when it comes to estrogen and progesterone. Estrogen, a sex hormone...

Navigating Hormonal Transitions: Women’s Health...

Understanding Hormonal Shifts During perimenopause and menopause, your body goes through a bit of a hormonal...

article-page-carousel-item--The Forgotten Foundations: Sleep, Sunlight, and Circadian Repair Pathways

The Forgotten Foundations: Sleep, Sunlight, and...

Effects of Aging on Your Biological Clock Your circadian rhythm is basically your body’s internal clock, guiding the natural 24-hour cycle of sleep, wakefulness, and a variety of physiological processes....

The Forgotten Foundations: Sleep, Sunlight, and...

Effects of Aging on Your Biological Clock Your circadian rhythm is basically your body’s internal clock,...

Variations in Nicotinamide Metabolism Impacts P...

Key Points:  Some participants had no NAM increase after supplementation An AD biomarker decreased in participants with increased NAM levels Individual differences in metabolism influenced responses to NAM supplementation NAM...

Variations in Nicotinamide Metabolism Impacts P...

Key Points:  Some participants had no NAM increase after supplementation An AD biomarker decreased in participants...