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Scientific Evidence Library
Neuroprotective Effects of NAD+ Nasal Spray
"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to brain tissues, thereby circumventing the hepatic first-pass metabolism and gastric degradation and allowing fast...
Neuroprotective Effects of NAD+ Nasal Spray
"Compared to traditional routes, the nasal administration of drugs can direct the rapid CNS absorption to...
NMN Reduced Cellular Aging and Improved Su...
This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation, mitochondrial function, and survival in mice.
NMN Reduced Cellular Aging and Improved Surviva...
This study evaluated the effects of intraperitoneal (i.p.) injections of NMN on tumor-induced cellular aging, inflammation,...
Higher NMN levels in breast milk linked to...
“NMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the first time, a positive relationship between NMN concentrations in breast milk and the neurodevelopmental...
Higher NMN levels in breast milk linked to bett...
“NMN had the highest concentrations in breast milk among the NAD-related substances. We demonstrated, for the...
NMN Enhances Spinal Cord Injury Recovery i...
“NMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways related to neurological diseases.”
NMN Enhances Spinal Cord Injury Recovery in Mice
“NMN exerts neuroprotective effects after SCI by the regulation of certain genes acting on signaling pathways...
High-Dose NR is Safe & Does Not Deplete Me...
This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in patients with Parkinson’s Disease (PD).
High-Dose NR is Safe & Does Not Deplete Methyl ...
This study evaluated the safety and effects of high-dose (3,000 mg) Nicotinamide Riboside (NR) supplementation in...
Clinical Trial Fails to Find Significant B...
This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI and effectively increased blood levels of NAD+.
Clinical Trial Fails to Find Significant Benefi...
This study showed that NR (1 g/day) for 10 weeks is safe in adults with MCI...
Deep Sleep May Protect Against Dementia
“These data from a community-based sample demonstrate that SWS percentage declines over time in adults 60 years and older and that greater declines are associated with the risk of future...
Deep Sleep May Protect Against Dementia
“These data from a community-based sample demonstrate that SWS percentage declines over time in adults 60...
Palmitoylethanolamide (P.E.A.) Reduces Inf...
This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation. “As our data demonstrated, the blunted synthesis of pro-inflammatory cytokines by PEA can stop this vicious cycle among...
Palmitoylethanolamide (P.E.A.) Reduces Inflamma...
This study showed that P.E.A. protected mice from HFD-induced anxiety-like behavior and inflammation. “As our data demonstrated,...
Study Finds NR Reaches the Brain & Improve...
“But until now, it was unknown whether NR reached targeted organs like the brain to have a real therapeutic effect,” according to Christopher Martens, one of the key researchers in...
Study Finds NR Reaches the Brain & Improves Neu...
“But until now, it was unknown whether NR reached targeted organs like the brain to have...
Increasing NMN Transporter in the Brain Re...
Doubling Slc128a Dramatically Improved Muscle Strength and Endurance It’s known that NMN transporters like Slc128a help to maintain NAD+ levels as we age. This caused researchers to speculate what may...
Increasing NMN Transporter in the Brain Reduces...
Doubling Slc128a Dramatically Improved Muscle Strength and Endurance It’s known that NMN transporters like Slc128a help...
Newly Found Benefits of Resveratrol in Hea...
Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance the activation of the body's own self-repair proteins, called sirtuins. When sirtuins are activated,...
Newly Found Benefits of Resveratrol in Health a...
Resveratrol is a polyphenol derived from plants with antioxidant properties that have been shown to enhance...
Increased NAD+ in Bloodstream of Nursing M...
These improvements in health and behavior persisted for the length of the study, which was 90 days after birth. Some quotes from the study: Adding NR to normal chow (NC)...
Increased NAD+ in Bloodstream of Nursing Mice R...
These improvements in health and behavior persisted for the length of the study, which was 90...