Research

Dogs and Humans Share Same Benefits from NMN Su...
Studies have shown the ability of NMN to elevate systemic levels of NAD+ in humans and ameliorate many of the diseases of old age. In a new study on dogs,...
Dogs and Humans Share Same Benefits from NMN Su...
Studies have shown the ability of NMN to elevate systemic levels of NAD+ in humans and...

NMN and Resveratrol Work Synergistically to boo...
A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+ levels in both heart and skeletal muscle tissues in mice. Combination treatments shown to...
NMN and Resveratrol Work Synergistically to boo...
A new study shows that the combination of NMN and Resveratrol works synergistically to increase NAD+...

NAD+ Reduces Mutations and Incidence of Skin Ca...
In a new study by Brown University School of Medicine, it was shown that oral nicotinamide (NAM) supplementation decreased the incidence of keratinocyte carcinoma (KC) in high-risk skin cancer patients....
NAD+ Reduces Mutations and Incidence of Skin Ca...
In a new study by Brown University School of Medicine, it was shown that oral nicotinamide...

NAD+ and the Hallmarks of Aging Series - Part 9...
All species of animals, including the human being, are multicellular organisms (an organism that consists of more than one cell).
NAD+ and the Hallmarks of Aging Series - Part 9...
All species of animals, including the human being, are multicellular organisms (an organism that consists of...

Exogenous NAD+ Increases Metabolism
Effects of Chronic NAD Supplementation on Energy Metabolism and Diurnal Rhythm in Obese Mice In a study published in 2018, scientists gave obese mice 1 mg/kg of NAD+ by inter...
Exogenous NAD+ Increases Metabolism
Effects of Chronic NAD Supplementation on Energy Metabolism and Diurnal Rhythm in Obese Mice In a...

Inhibition of CD38 Increases NAD+ Levels
CD38 Increases as We Age and Drives Down NAD+ Levels CD38 is an enzyme that responds to inflammation, and consumes NAD+. Researchers have long known that CD38 levels increase, and...
Inhibition of CD38 Increases NAD+ Levels
CD38 Increases as We Age and Drives Down NAD+ Levels CD38 is an enzyme that responds...

NMN Triples NAD+ Levels in Humans
(Pencina et al., 2022 | The Journals of Gerontology) NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels...
NMN Triples NAD+ Levels in Humans
(Pencina et al., 2022 | The Journals of Gerontology) NMN doses of 1,000 mg taken once...

NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice daily, NMN triples NAD+ levels (right graph). Dr. David Sinclair is a co-founder of...
NMN Triples NAD+ Levels in Humans
NMN doses of 1,000 mg taken once daily doubles NAD+ levels (middle graph). When taken twice...

Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR). However, Dr. Sinclair recently said he takes NMN instead of NR...
Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and...

Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR). However, Dr. Sinclair recently said he takes NMN instead of NR...
Why Dr. Sinclair takes NMN instead of NR
There has been little, if any, head to head research published comparing Nicotinamide Mononucleotide (NMN) and...

Lower Inflammation to Raise NAD+
Results from hundreds of tests for Intracellular NAD+ levels tell us that those with high inflammation levels (measured by HS-CRP) have less success raising NAD+ levels.Lowering inflammation can help restore...
Lower Inflammation to Raise NAD+
Results from hundreds of tests for Intracellular NAD+ levels tell us that those with high inflammation...

NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark of aging and is a major cause of decreased tissue homeostasis in the old...
NAD+ and the Hallmarks of Aging Series – Part 8...
Altogether, these studies suggest that the decline of stem cell number and function is a hallmark...