Research
Reduced Nicotinamide Mononucleotide - A Tale of...
NAD+ Precursors and Healthy Aging Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells. It is a critical coenzyme for energy metabolism and also serves as the...
Reduced Nicotinamide Mononucleotide - A Tale of...
NAD+ Precursors and Healthy Aging Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living...
Study Shows NMN Supplementation or CD38 Inhibit...
CD38 Deficiency Alleviates Ang II-Induced Vascular Remodeling By Inhibiting Small Extracellular Vesicle-Mediated Vascular Smooth Muscle Cell Senescence In Mice (Lu Gan, June 2021) In this study, researchers investigated the impact...
Study Shows NMN Supplementation or CD38 Inhibit...
CD38 Deficiency Alleviates Ang II-Induced Vascular Remodeling By Inhibiting Small Extracellular Vesicle-Mediated Vascular Smooth Muscle Cell...
Bacteria in Gastrointestional Tract Metabolize ...
This recently published research by Drs. Lindsay Wu, David Sinclair and others examined the pathways that oral NMN takes to becoming NAD+ in mice. It confirmed some aspects of earlier...
Bacteria in Gastrointestional Tract Metabolize ...
This recently published research by Drs. Lindsay Wu, David Sinclair and others examined the pathways that...
CD73 utilization shows importance of NMN to res...
This recent study found that in endothelial cells, the extracellular conversion of NMN to NR by CD73 enzyme in the cell membrane is a key mechanism to maintain intracellular NAD+...
CD73 utilization shows importance of NMN to res...
This recent study found that in endothelial cells, the extracellular conversion of NMN to NR by...
Case Study on Liposomal NMN Shows Positive Impa...
“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited remarkable protective effects against hepatic tissue damage, steatosis, inflammation, insulin resistance, and hepatocellular enzyme...
Case Study on Liposomal NMN Shows Positive Impa...
“In an animal model of type 2 diabetes, the intragastric delivery of Lip-BBR via liposomes exhibited...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be...
1st NMN Human Study Demonstrates Safety and Fas...
The single oral administration of NMN was safe and effectively metabolized in healthy men without causing...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of 3 μmole/min all exogenously infused NAD+ was rapidly and completely removed from the plasma...
NAD+ IV increases NAD+ levels in blood plasma 4...
In summary, this study revealed for the first time that: (a) at a flow rate of...
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport a small quantity of Nicotinamide Mononucleotide (NMN) directly into some cells.
Slc12a8 Does not Solve the Bioavailability Prob...
This research was published in January 2019 that found an enzyme named Slc12a8 that can transport...
Scientists discover SLC12a8 pathway used by NMN...
Yes, NMN can cross the cell membrane intact This research was just published that found an enzyme named Slc12a8 that can transport a small quantity of Nicotinamide Mononucleotide (NMN) directly...
Scientists discover SLC12a8 pathway used by NMN...
Yes, NMN can cross the cell membrane intact This research was just published that found an...
NAD+ for Metabolism and Brain, NMN for the body?
Researchers use supplementation with NMN, NR and NAD⁺ to restore levels of NAD⁺ in mice, making them look and behave like they did when young and extending their lifespan. Although...
NAD+ for Metabolism and Brain, NMN for the body?
Researchers use supplementation with NMN, NR and NAD⁺ to restore levels of NAD⁺ in mice, making...