A meta-analysis of five studies concluded that CoQ10 supplementation is more effective than a placebo in reducing migraine occurrence and duration in both children and adults.

“The results support the use of CoQ10 as a potent therapeutic agent with respect to migraine duration and migraine days/month.” (Zeng et al., 2018)

These findings were corroborated in a subsequent meta-analysis of six clinical trials that showed CoQ supplemented as a preventative measure was effective for reducing the duration and frequency of migraines.