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EGCG from Green Tea Protects Motor Control and Mood in Mice
This
study examined the effects of pretreating mice with EGCG to delay destruction of dopamine-sensitive brain cells to promote mobility and stable moods.
In a mouse model of Parkinson's Disease, mice that were pretreated with EGCG showed the least damage to neurons, had higher mood stability, and maintained more motor movement control.
In this figure, the white bars represent the number of TH immune-positive cells, a measure of healthy dopamine-sensitive cells.
Mice with damaged brain cells (PFFs group) experienced a 58% decrease in dopamine-sensitive cells compared to healthy mice (Sham group), where the EGCG pretreatment group (EGCG+PFFs group) only experienced a 36% loss in these cells.
EGCG pretreatment prevented the accumulation of α-synuclein preformed fibrils, a type of protein associated with Parkinson’s Disease and known to severely impair brain function.
Liposomal Delivery
Traditional EGCG is poorly absorbed, only 5-10% is taken up after digestion; LIPO Green Tea solves this problem, and enhances bioavailability to over 90%.
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STUDY: Trigonelline - An NAD+ precursor that improves muscle function during ageing
RESEARCH
A recent study has looked at how trigonelline, a compound found in certain foods, can improve overall muscle function as one ages.
The researchers found that trigonelline enhanced NAD+ levels in the body and mitigated age-related decline in muscle strength and endurance.