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Exciting Research on NAD+ Nasal Spray



A recent research review analyzed studies on intranasal delivery as a potential therapeutic for mitochondrial dysfunction associated with brain injuries and other central nervous system disorders. 
 
The traditional routes of administration are limited by the blood brain barrier (BBB). 
 
Intranasal delivery bypasses the BBB and quickly delivers the active ingredients directly to the brain through the olfactory and trigeminal nerves.
 
Here we'll share some highlights from the research involving intranasal delivery of NAD+ for brain injuries in mice. 
Graphics from the study: (Pandya, J.D., Musyaju, S., Modi, H.R. et al., 2024 | Journal of Translational Medicine) 

What the Studies Revealed

  • Reduced brain injury in rats after stroke
  • Prevented brain cell death in rats after head injury
  • Slowed down the progression of brain infection in mice

This figure illustrates the neurological function assessed 24 hours after the stroke.
 
Rats receiving intranasal NAD+ (white bar) exhibited markedly fewer neurological deficits compared to untreated rats (black bar).


Visit LongevityClips for the full research review.

Disclaimer:

This email references ongoing research and it's important to note that:

  • This research is preliminary and has been conducted solely in animal models (mice and rats).

  • No human studies have been published on nasal administration of NAD+ or NAD precursors.

  • Further studies, including clinical trials in humans, are required to determine potential efficacy in humans.

The information should not be interpreted as any guarantee or claim regarding the effectiveness of any product, including those offered by our company.

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