Meta-Review: NMN Promotes Liver and Muscle Health in Middle Aged and Older Adults
This meta-review found that NMN improves muscle function, reduces insulin resistance, and lowers liver enzyme levels in middle-aged and elderly participants:
NMN Improved Metabolic Function and Ovarian Health in Aged Mice
A recent study in mice investigated the effects of short- and long-term NMN supplementation on age-related fertility decline and ovarian health:
This graph shows that aged mice (pink bar) produced significantly fewer eggs (oocytes) than young mice (yellow bar), but when given NMN (purple bar), the aged mice produced significantly more eggs compared to untreated aged mice.
Hello, I've been using these products now for 3 years and since the introduction of the liposome delivery method I have not heard anyone talk about whether dosage should be lowered. If NMN, for example, is recommended at 1000 mg/day, would 500 mg/day with liposome delivery be as good or better? I don't want to overdo it (for health and cost both!). Same for other molecules as well. I try to follow Dr. David Sinclair's protocol, but without knowing if he uses the liposomal delivery or not, it's hard to know what to do. Thank you!
Heather L. Makar is a biologist, longevity futurist, TEDx speaker, and science writer focused on translating complex mechanisms of aging into strategies for healthspan extension. At Renue By Science, she leads research-driven content strategy that empowers readers to understand, optimize, and evolve their own biology. She brings a multidisciplinary perspective to health optimization, bridging natural medicine and cutting edge science to build actionable protocols that have tangible effects immediately and far into the future.
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